Running a marathon can increase cardiac strain in amateur runners
Journal of the American Heart Association Report
- Amateurs running full-length marathons could be significantly raising levels of several key biomarkers of cardiac strain.
- Levels of two proteins – troponin I and troponin T– were highest after runners completed a full marathon compared to a half marathon, and a 10K race, as were other biomarkers of cardiac stress.
Embargoed until 4 a.m. CT / 5 a.m. ET Monday, December 3, 2018
DALLAS, December 3, 2018 —Full marathons may significantly raise concentrations of several biomarkers of strain on the heart, according to new research in Circulation, Journal of the American Heart Association.
Investigators in Spain compared levels of cardiac biomarkers, including – troponin I and troponin T- in 21 groups of 3 runners each after each individually ran an endurance race of three different lengths – a full marathon, a half marathon and a 10K race. All of the 63 subjects were amateur runners. They also measured levels of biomarkers for cardiac tissue stress.
Although there was little difference in 10-year risk for cardiovascular events between the runners (average about 3 percent), the strain on the heart muscle, as measured by the biomarker levels, was much greater after a full marathon.
The incidence of cardiac arrests in marathoners is only about 1 in 50,000 runners who compete in races, but a high proportion of all exercise-induced cardiac events occur during marathons, especially in men 35 years of age and older.
The number of subjects in the study was not large enough to accurately assess differences in 10-year cardiovascular risk, but the researchers are planning to examine this in a larger group of runners, said lead investigator Juan Del Coso, Ph.D., director of the exercise physiology laboratory at Camilo José Cela University, in Madrid, Spain.
“We typically assume that marathon runners are healthy individuals, without risk factors that might predispose them to a cardiac event during or after a race. But with the growing popularity of long-endurance races, the exponential increase in the number of participants, and the lack of appropriate training in some cohorts of amateur runners, our findings suggest that running shorter endurance races might reduce the strain imposed on the myocardium during running competition,” Del Coso said.
Co-authors are Beatriz Lara, Ph.D.; Juan José Salinero Ph.D.; César Gallo-Salazar Ph.D.; Francisco Areces Ph.D.; Diana Ruiz-Vicente Ph.D.; and Manuel Martinez, M.Sc. Author disclosures are on the manuscript.
The Vice-Rectorate of Innovation of Camilo José Cela University (HEART project) supported the study.
- Avaialble multimedia available on the right column of the release link: https://newsroom.heart.org/news/running-a-marathon-can-increase-cardiac-strain-in-amateur-runners?preview=5c779999bba3348ce7404a5d86f18c3b
- After December 3, view the manuscript online.
- For more information on heart failure, visit RiseAboveHF.org.
- Follow AHA/ASA news on Twitter @HeartNews
Statements and conclusions of study authors published in American Heart Association scientific journals are solely those of the study authors and do not necessarily reflect the association’s policy or position. The Association makes no representation or guarantee as to their accuracy or reliability. The Association receives funding primarily from individuals. Foundations and corporations (including pharmaceutical, device manufacturers and other companies) also make donations and fund specific association programs and events. The Association has strict policies to prevent these relationships from influencing the science content. Revenues from pharmaceutical and device corporations and health insurance providers are available at https://www.heart.org/en/about-us/aha-financial-information.
About the American Heart Association
The American Heart Association is a leading force for a world of longer, healthier lives. With nearly a century of lifesaving work, the Dallas-based association is dedicated to ensuring equitable health for all. We are a trustworthy source empowering people to improve their heart health, brain health and well-being. We collaborate with numerous organizations and millions of volunteers to fund innovative research, advocate for stronger public health policies, and share lifesaving resources and information. Connect with us on heart.org, Facebook, Twitter or by calling 1-800-AHA-USA1.
For Media Inquiries and AHA/ASA Spokesperson Perspective: 214-706-1173
Carrie Thacker: 214-706-1665; firstname.lastname@example.org
For Public Inquiries: 1-800-AHA-USA1 (242-8721)