Struggles with sleep may affect heart disease risk

American Heart Association Rapid Access Journal Report

September 10, 2015 Categories: Heart News

Study Highlight

  • Young and middle-aged adults who get too much or too little sleep or have poor quality sleep are at higher risk for the early signs of heart disease than those who get adequate, good quality sleep.

Embargoed until 3 p.m. CT / 4 p.m. ET Thursday, Sept. 10, 2015

DALLAS, Sept. 10, 2015 — Are you getting enough quality sleep? Are you sleeping longer than you should? Poor sleep habits may put you at higher risk for early signs of heart disease when compared to those who get adequate, good quality sleep, according to a study published in the American Heart Association journal Arteriosclerosis, Thrombosis and Vascular Biology.

“Inadequate sleep is a common problem and a likely source of poor health, including visible signs of disease, such as heart attack,” said Chan-Won Kim, M.D., study co-lead author and clinical associate professor in the Center for Cohort Studies at Kangbuk Samsun Hospital, Sungkyunkwan University School of Medicine in Seoul, South Korea.

Researchers studied more than 47,000 young and middle-aged adults who completed a sleep questionnaire and had advanced tests to detect early coronary artery lesions and measure arterial stiffness. Early coronary lesions were detected as the presence of calcium in the coronary arteries and arterial stiffness was assessed by measuring the velocity, or speed, of the pulse wave between the arteries in the upper arm and ankle.

After measuring coronary calcium, researchers found:

  • Adults who sleep five or fewer hours a day have 50 percent more calcium in their coronary arteries than those who sleep seven hours a day.
  • Those who sleep nine or more hours a day have more than 70 percent more coronary calcium compared to those who sleep seven hours.
  • Adults who reported poor sleep quality had more than 20 percent more coronary calcium than those who reported good sleep quality.

“We also observed a similar pattern when we measured arterial stiffness,” said Yoosoo Chang, M.D., Ph.D., study co-lead author and associate professor in the Center for Cohort Studies at Kangbuk Samsun Hospital. “Adults with poor sleep quality have stiffer arteries than those who sleep seven hours a day or had good sleep quality. Overall, we saw the lowest levels of vascular disease in adults sleeping seven hours a day and reporting good sleep quality.”

The study’s findings highlight the importance of adequate sleep quantity and quality to maintain cardiovascular health.

“For doctors, it might be necessary to assess patients’ sleep quality when they evaluate the cardiovascular risk and the health status of men and women,” Kim said.

The self-reported assessments of sleep duration and quality in the study may underestimate the cardiovascular risk, researchers said.

Other co-authors are Di Zhao, Ph.D.; Miguel Cainzos-Achirica, M.D.; Seungho Ryu, M.D., Ph.D.; Hyun-Suk Jung, M.D.; Kyung Eun Yun, M.D., Ph.D.; Yuni Choi, B.S.; Jiin Ahn, M.S.P. H.; Yiyi Zhang, Ph.D.; Sanjay Rampal, M.D., Ph.D.; Youngji Baek, M.P.H.; Joao A. Lima, M.D., Ph.D.; Hocheol Shin, M.D., Ph.D.; Eliseo Guallar, M.D., Dr.P.H.; Juhee Cho, Ph.D.; and Eunju Sung, M.D., Ph.D. Author disclosures are on the manuscript.

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